Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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271
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285
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271
Tocris Bioscience™ Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Cereblon ligand with terminal piperidine for onward chemistry
272
Tocris Bioscience™ AKOS 022
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Voltage-dependent anion channel (VDAC) inhibitor
| Target | Ion Channel Modulators |
|---|---|
| CAS | 878983-38-1 |
| Purity | 0.98 |
| Chemical Name or Material | 1-(4-Chlorophenyl)-3-[4-[[4-(trifluoromethoxy)phenyl]amino]-1-piperidinyl]-2,5-pyrrolidinedione |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H21ClF3N3O3 |
273
Tocris Bioscience™ Pomalidomide 4'-PEG3-azide
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Cereblon ligand with PEG linker and terminal azide for onward chemistry
274
Tocris Bioscience™ CTPI 2
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective mitochondrial citrate transporter (SLC25A1) inhibitor
| Target | Other Ion Pump/Transporter Inhibitors |
|---|---|
| CAS | 68003-38-3 |
| Purity | 98% |
| Chemical Name or Material | 2-[[(4-Chloro-3-nitrophenyl)sulfonyl]amino]benzoic acid |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C13H9ClN2O6S |
275
Tocris Bioscience™ CBA
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective TRPM4 blocker
| CAS | 351424-20-9 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 4-Chloro-2-[[2-(2-chlorophenoxy)acetyl]amino]benzoic acid |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C15H11Cl2NO4 |
| Formula Weight | 340.16 |
276
Tocris Bioscience™ VH 101 phenol-alkylC4-amine
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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VHL ligand with alkyl linker and terminal amine for onward chemistry
277
| CAS | 51481-61-9 |
|---|---|
| Molecular Formula | C10H16N6S |
279
280
Tocris Bioscience™ CELT-211
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Fluorescent serotonin 5HT2B receptor ligand for HTS
281
Tocris Bioscience™ Ac4GalN6yne
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Alkyne containing monosaccharide building block; used in BOCTAG
282
Tocris Bioscience™ LEI 401
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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High affinity N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) inhibitor
284
Tocris Bioscience™ Pexacerfont
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Potent and selective CRF1 antagonist; anxiolytic
| CAS | 459856-18-9 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 8-(6-Methoxy-2-methyl-3-pyridinyl)-2,7-dimethyl-N-[(1R)-1-methylpropyl]pyrazolo[1,5-a]-1,3,5-triazin-4-amine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C18H24N6O |
| Formula Weight | 340.43 |
285
Tocris Bioscience™ AS 1842856
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective Foxo1 inhibitor; orally bioavailable
| CAS | 836620-48-5 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 5-Amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid |
| Molecular Formula | C18H22FN3O3 |