Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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285
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271
Tocris Bioscience™ ONO 8130
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EP1 receptor antagonist
| CAS | 459841-96-4 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Solubility | Soluble to 100mM in DMSO and to 20mM in ethanol |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | ONO 8130 |
| Recommended Storage | Store at 4°C |
| Synonym | 4-[[[2,3-Dihydro-6-[(2-methylpropyl)[(4-methyl-2-thiazolyl)sulfonyl]amino]-1H-indene-5yl]oxy]methyl]benzoic acid |
| Molecular Formula | C25H28N2O5S2 |
| Formula Weight | 500.63 |
272
Tocris Bioscience™ SL 327
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CAS: 305350-87-2 Molecular Formula: C16H12F3N3S
| CAS | 305350-87-2 |
|---|---|
| Molecular Formula | C16H12F3N3S |
273
Tocris Bioscience™ GeA-69
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Selective allosteric PARP14 inhibitor
| Target | PARP |
|---|---|
| CAS | 2143475-98-1 |
| Purity | 0.98 |
| Chemical Name or Material | N-[2-(9 H-Carbazol-1-yl)phenyl]acetamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C20H16N2O |
274
Tocris Bioscience™ GR 203040
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Potent, selective NK1 receptor antagonist
| CAS | 168398-02-5 |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Synonym | (2S,3S)-N-[[2-Methoxy-5-(1H-tetrazol-1-yl)phenyl]methyl]-2-phenyl-3-piperidinamine dihydrochloride |
| Molecular Formula | C20H24N6O.2HCl |
| Formula Weight | 437.37 |
275
Tocris Bioscience™ Antalarmin hydrochloride
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CAS: 220953-69-5 Molecular Formula: C24H35ClN4
| CAS | 220953-69-5 |
|---|---|
| Molecular Formula | C24H35ClN4 |
276
Tocris Bioscience™ CIA 1
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COUP-TFII inhibitor
| Target | Additional Nuclear Receptor Compounds |
|---|---|
| CAS | 1049691-47-5 |
| Purity | 0.98 |
| Chemical Name or Material | N-[2-(3,4-Dimethoxyphenyl)ethyl]-6-methylthieno[2,3-d]pyrimidin-4-amine hydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C17H19N3O2S.HCl |
277
Tocris Bioscience™ EG 00229 trifluoroacetate
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Neuropilin 1 (NRP1) receptor antagonist; inhibits VEGFA binding to NRP1
278
Tocris Bioscience™ Idelalisib
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Potent PI 3-Kinase δ isoform inhibitor
| Target | PI 3-Kinase Inhibitors |
|---|---|
| CAS | 870281-82-6 |
| Purity | 98% |
| Chemical Name or Material | 5-Fluoro-3-phenyl-2-[(1 S)-1-(9 H-purin-6-ylamino)propyl]-4(3 H)-quinazolinone |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H18FN7O |
279
Tocris Bioscience™ Heclin
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HECT E3 ubiquitin ligase inhibitor
| Inhibitors | Heclin |
|---|---|
| Product Type | Heclin |
| Molecular Weight (g/mol) | 283.32 |
| Purity | >98% |
280
Tocris Bioscience™ GBR 12783 dihydrochloride
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CAS: 67469-75-4 Molecular Formula: C28H34Cl2N2O
| CAS | 67469-75-4 |
|---|---|
| Molecular Formula | C28H34Cl2N2O |
281
Tocris Bioscience™ Tranilast
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 53902-12-8 Molecular Formula: C18H17NO5
| CAS | 53902-12-8 |
|---|---|
| Molecular Formula | C18H17NO5 |
282
Tocris Bioscience™ A 412997 dihydrochloride
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Selective D4 agonist
| CAS | 1347744-96-0 |
|---|---|
| Chemical Name or Material | N-(3-Methylphenyl)-4-(2-pyridinyl)-1-piperidineacetamide |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C19H23N3O.2HCl |
| Formula Weight | Observed MW: 382.33 |
| Assay Percent Range | >98% |
283
Tocris Bioscience™ GC 1
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CAS: 211110-63-3 Molecular Formula: C20H24O4
| CAS | 211110-63-3 |
|---|---|
| Molecular Formula | C20H24O4 |
284
Tocris Bioscience™ 4EGI-1
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CAS: 315706-13-9 Molecular Formula: C18H12Cl2N4O4S
| CAS | 315706-13-9 |
|---|---|
| Molecular Formula | C18H12Cl2N4O4S |
285
Tocris Bioscience™ K 114
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CAS: 872201-12-2 Molecular Formula: C22H17BrO2
| CAS | 872201-12-2 |
|---|---|
| Molecular Formula | C22H17BrO2 |